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  1. Both losartan and its principal active metabolite have hydrochlorothiazide 12.5 mg a far greater affinity for the AT1 receptor than for the AT2 receptor. If calcium supplements must be prescribed, hydrochlorothiazide 12.5 mg serum calcium levels should be monitored and calcium dose should be adjusted accordingly.

  2. This Diovan HCT price guide is based on using the m discount card which is accepted at hydrochlorothiazide 25 mg most.S. Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit.